COM'on Case 29
A 62-year-old male developed aortic valve stenosis. Surgery was performed.
SCVP thanks Dr. Joseph Maleszewski for this case.
Images of the case are seen here.
Do you know what it is? Submit your diagnosis here and we'll let you the know the correct diagnosis next month.
Click here for the answer.
Click here for a discussion of the entity.
Ochronosis of the aortic valve is a manifestation of chronic alkaptonuira that is the caused by deposition of bluish-black pigment consisting of oxidized homogentisic acid. The metabolic derangement is the result of a recessive trait. Pigment can deposited in intervertebral discs, cartilage, skin and cardiac valves (particularly the aortic and mitral valves). Heavy calcification is often seen in association with the pigment (as in this case) and there is a general belief that the pigment hastens development of both atherosclerosis and calcification. This may, in part, explain the relatively young age (60-years-old) that this patient developed hemodynamically significant (tricuspid) aortic valve stenosis, which is usually seen in the 8th or 9th decades of life.
COM'on Main Page | Previous COM'on case | Next case
Have a case you'd like us to use for a COM'on? Contact the SCVP Webmaster and let us know.