A 67-year-old woman developed recurrent pericardial effusions. Repeated cytology of the effusion showed inflammatory cells and was negative for malignancy. Systolic heart failure increased and the subject underwent pericardial fenestration. Biopsy materials of the epicardium was collected at that time.
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Metastatic lobular breast carcinoma.
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A lobular carcinoma of the breast represents one of the most common secondary heart tumors. Pericardial involvement with recurrent effusions is one of the typical clinical presentations. However, no physical or laboratory examination can specifically detect cardiac metastases in case of diffuse disease. Therefore, it can be easily misdiagnosed as a myocarditis or another non-neoplastic condition.
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